Possible Role of Noggin Gene in Mandibular Development / Posible papel del gen noggin en el desarrollo mandibular

Polymorphisms of the noggin gene and mandibular micrognathia: a first approximation.

Mandibular micrognathia is a deficiency in mandibular growth that prevents tooth contact during mastication, interferes with phonation and even causes sleep apnea. Studies show that mutant mice for chd (chordin) and nog (noggin) genes, which are modulators of the Bone Morphogenic Protein (BMP), had mandibular defects ranging from mandibular hypoplasia to micrognathia and agnathia. The human NOG...

Causas del desarrollo de exceso de peso en el adolescente

In the natural history of type 2 diabetes, pancreatic insulin secretion is progressively depleted and metabolic control worsens. Treatment of these patients usually starts with diet and exercise, with subsequent use of oral glucose-lowering drugs, finally ending with insulin therapy to achieve good metabolic control. When there is still endogenous insulin secretion, the combination of insulin a...

The BMP antagonists Chordin and Noggin have essential but redundant roles in mouse mandibular outgrowth.

Here we investigate the roles of the Bone Morphogenetic Protein (BMP) antagonists Chordin and Noggin in development of the mandible, which is derived from the first branchial arch (BA1). Both genes are expressed in the pharynx during early mandibular outgrowth and later in the mandibular process. Mice mutant for either Nog or Chd have only mild mandibular defects; however, pups of the genotype ...

La Detección Y El Desarrollo Del Talento En El Fútbol: Una Revisión Talent Detection and Development in Soccer: a Review

Considerando el Enfoque del Diseño de Microinteracciones como Aspecto Clave en el Desarrollo de Software

Resumen. La búsqueda de la perfección en el diseño de nuevas tecnologías ha impulsado la concepción de nuevos enfoques y entender los distintos y variados fenómenos envueltos en este proceso evolutivo. Vivimos en un mundo donde los mínimos detalles, las pequeñas cosas y los breves instantes son ya considerados realmente relevantes; esta aseveración se ha formado a partir de los descubrimientos ...